Dr Alexandre Akoulitchev
Clinical Support Advisor · MA, PhD, FRSM
Dr Alexandre Akoulitchev is a molecular biologist who specialises in gene regulation and the three-dimensional structure of the genome.
He earned a PhD in cell biology at University College London, then spent six years as a researcher at Robert Wood Johnson Medical School in New Jersey, funded by the Howard Hughes Medical Institute. From 2000 to 2007 he was a Research Fellow at the Sir William Dunn School of Pathology, University of Oxford, where his work on chromosome conformation signatures led to the EpiSwitch blood-test technology.
In 2007 he co-founded Oxford BioDynamics, where he is Chief Scientific Officer. He has been a Senior Research Fellow of Exeter College, Oxford, is a named inventor on a number of patents and is a Fellow of the Royal Society of Medicine.
Education and qualifications
- PhD in Cell Biology, University College London
- MA, University of Oxford (MA Oxon)
- Studied at the Moscow Institute of Physics and Technology
Experience
- Co-founder and Chief Scientific Officer, Oxford BioDynamics (from 2007)
- Research Fellow, Sir William Dunn School of Pathology, University of Oxford (2000 to 2007)
- Senior Research Fellow, Exeter College, Oxford (past)
- Researcher, Robert Wood Johnson Medical School, New Jersey (Howard Hughes Medical Institute funded)
Professional memberships
- Fellow of the Royal Society of Medicine
Selected publications
- Repression of the human dihydrofolate reductase gene by a non-coding interfering transcript. Nature, 2007
- TFIIH is negatively regulated by cdk8-containing mediator complexes. Nature, 2000
- Methods for detecting long range interactions in chromatin. Patent WO 2009/147386
Areas of expertise
- Epigenetics
- Gene regulation
- Advanced diagnostics