Non Invasive Prenatal Testing (NIPT) - PrenatalSAFE Karyo is a groundbreaking method used to assess the risk of certain genetic disorders in a fetus, such as Down syndrome. This testing method is non-invasive, meaning that it involves a simple blood draw from the mother. Because of this, there are no risks associated with amniocentesis or chorionic villus sampling, which can be more invasive and carry potential complications. NIPT uses advanced DNA analysis to evaluate fragments of fetal DNA present in the mother's bloodstream, providing a reliable indicator of chromosomal abnormalities.
One of the main benefits of PrenatalSAFE Karyo is its high accuracy rate, often exceeding 99% in detecting conditions like Down syndrome. However, it is essential to understand that while NIPT can indicate the likelihood of genetic conditions, it is not a diagnostic test. Therefore, a positive result should be followed up with further testing to confirm any findings. Many expectant parents appreciate the peace of mind NIPT provides, as it allows for earlier interventions or informed decision-making during pregnancy.
NIPT is recommended for various groups, including women aged 35 and older, those with a history of genetic disorders, or anyone interested in early prenatal screening. Because NIPT is both safe and effective, many healthcare providers suggest it as a primary screening option for chromosomal abnormalities. The test can be performed as early as the 10th week of pregnancy, making it a proactive choice for parents-to-be who want to ensure the health of their baby.
By analysing small fragments of your baby’s DNA present in your blood, this test screens for a wide range of chromosomal conditions, including:
Down syndrome (Trisomy 21)
Edwards syndrome (Trisomy 18)
Patau syndrome (Trisomy 13)
Turner syndrome (Monosomy X)
Klinefelter syndrome
Jacobs syndrome
Autosomal aneuploidies, duplications & deletions
Gender identification (available for single pregnancies and identical twins)
For complete peace of mind, free post-test genetic counselling is included if your results indicate an increased chance of a condition, ensuring you receive expert guidance and support when you need it most.
In the case of Dichorionic Twin pregnancies, and vanishing twin, sex chromosome aneuploidies (SCA’s) cannot be reported.
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Compare NIPT tests
All Goodbody NIPT tests use a simple, safe blood sample from 10 weeks. The right one for you depends on how much you want to know.
| Compare tests | PrenatalSAFE 3 The essentials From £315 View test | PrenatalSAFE 5 Adds sex chromosomes From £375 View test | PrenatalSAFE Karyo All 23 chromosome pairs From £645 Your selection | Most popularPrenatalSAFE Karyo Plus Adds 9 microdeletions From £795 Upgrade | Most comprehensivePrenatalSAFE Complete Plus Most comprehensive From £1,545 Upgrade |
|---|---|---|---|---|---|
| Conditions screened | 3 | 7 | 10 | 19 | 21+ |
| Down, Edwards & Patau syndrome Trisomy 21, 18 & 13 | |||||
| Sex chromosome disorders Turner, Klinefelter, Jacobs | |||||
| All 23 chromosome pairs Aneuploidies, deletions & duplications | |||||
| 9 microdeletion syndromes Prader-Willi, Angelman, DiGeorge & more | |||||
| 5 inherited genetic diseases Cystic fibrosis, sickle cell, thalassemia, deafness | |||||
| ~50 De Novo diseases Spontaneous mutations not inherited from parents | |||||
| Gender identification Single pregnancies & identical twins | |||||
| Twin pregnancy | |||||
| Results turnaround | 3–5 working days | 3–5 working days | 5–7 working days | 10–12 working days | Staged: 10 & 20 working days |
| From pregnancy week | 10 weeks | 10 weeks | 10 weeks | 10 weeks | 10 weeks |
| Sample collection | In-clinic or at home | In-clinic or at home | In-clinic or at home | In-clinic or at home | In-clinic or at home |
| Free post-test genetic counselling Included with every positive result | |||||
| Price (from) | £315 | £375 | £645 | £795 | £1,545 |
| Choose test | Choose | Choose | Your selection | Choose | Choose |
All prices are for in-clinic appointments. Home visits available at a small additional cost. Free post-test genetic counselling is included with every test should a positive result arise.
Meet the clinical lead
This is the safest and easiest way to find out the gender or check the genetic health of your baby during pregnancy, with FREE genetic counselling provided if you receive a positive result for any health condition. We provide a specialised testing kit to take with you to your appointment and a FREE pre-consultation on Karyo, Karyo Plus, and Complete Plus Tests.
Book online, receive your kit and take to your local Goodbody clinic.
Send your sample in the post to be analysed at an accredited laboratory.
Get your comprehensive detailed results report from the laboratory, with guidance from our support team.
Suitable for women of all ages, of at least 10 weeks of gestation (at the time of their blood draw appointment), who have had their pregnancy type (single or twin) previously confirmed by an ultrasound scan. The pregnancy can be naturally conceived or through IVF.
Our genetic health tests are called NIPT tests, or Non-Invasive Prenatal Tests. An NIPT is a blood test taken from the mother during pregnancy, using state of the art DNA technology to check whether the baby has high risks of certain chromosomal health conditions.
During pregnancy the placenta sheds cell free DNA (cfDNA) into the mother’s bloodstream. This means that the mother’s blood continues a mixture of your own DNA, and that of your baby’s placenta. By extracting and evaluating the cfDNA in your blood, we can identify the risk to your baby of a range of health conditions and diseases.
Enquire via the form and a member of our team will get back to you, they are more than happy to help answer your questions and talk through the best option for you.
Contact us if you aren't sure, we'd be happy to help!
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AFTER YOUR TEST
When you’re worried about your health, life can feel very stressful, especially if you don’t have the answers you need. We believe that health testing should be available to all, giving you answers when and where you need them.
That’s why we’ve partnered with Splitit, Dopple and Clearpay so you can pay for your tests in interest-free instalments, if you prefer.